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Adjunct antibody administration with standard treatment reduces relapse rates in a murine tuberculosis model of necrotic granulomas

In conclusion, eryptosis targeting is a promising therapeutic approach in multiple human diseases that should not be neglected

Foreman KJ, Marquez N, Dolgert A, Fukutaki K, Fullman N, McGaughey M, Pletcher MA, Smith AE, Tang K, Yuan CW, Brown JC, Friedman J, He J, Heuton KR, Holmberg M, Patel DJ, Reidy P, Carter A, Cercy K, Chapin A, Douwes-Schultz D, Frank T, Goettsch F, Liu PY, Nandakumar V, Reitsma MB, Reuter V, Sadat N, Sorensen RJD, Srinivasan V, Updike RL, York H, Lopez AD, Lozano R, Lim SS, Mokdad AH, Vollset SE, Murray CJL

In addition to their role in detoxification, bacterial GSTs are also involved in other metabolic processes like the degradation of lignin (Allocati et al., GSTs in Plant-virus Interactions Plant viruses are obligate biotrophic pathogens that need living tissues for their multiplication